TECHNOLOGY · RECORNA

Targeted RNA Editing
Technology Platforms

RecoRNA (Guangzhou) Biotechnology Co., Ltd

Xu Xin (Hong Kong) Biotechnology Co., Ltd

RecoRNA (Guangzhou) Biotechnology Co., Ltd, is a pioneering company developing RNA-targeted editing technologies to address diseases that currently lack effective treatments. We focus on unmet clinical needs across genetic diseases, neurological disorders, chronic conditions, and other therapeutic areas, advancing precision medicine through cutting-edge RNA-based innovations.

RecoRNA has built a comprehensive RNA therapy platform that includes a world leading single-base RNA editing design engine powered by the industry’s largest ADAR natural substrate library, an RNA fragment excision tool, and the AI driven ATOMIC screening platform. These breakthrough technologies enable the discovery and development of novel therapeutics that overcome the limitations of traditional small-molecule and biologic drugs. Our platforms are designed to address major challenges across frameshift mutation diseases, point mutation genetic disorders, metabolic diseases and Immuno-oncology–addressable cancers, while avoiding the irreversible off target safety risks associated with DNA level gene editing therapies.

Xu Xin (Hong Kong) Biotechnology Co., Ltd., a wholly-owned subsidiary of RecoRNA (Guangzhou) Biotechnology Co., Ltd, is located in the Hong Kong Science & Technology Park. The company has built an AI-driven technology platform that overcomes key bottleneck in traditional drug R&D and accelerates the entire process from target identification to hit-molecule design, lead optimization, and candidate selection.

RECORNA Laboratory

Core Technology Platforms

ATOMIC Platform

AI-driven R&D Platform

    Target Identification: Powered by the ATOMIC platform, the whole process from target discovery to POC (proof-of-concept) validation is significantly accelerated.

    Molecule Design and Optimization: With AI assistance, the efficiency and success rate of drug molecule design and lead optimization are greatly improved.

    Preclinical and Clinical Development: Through AI driven analysis, the efficacy and PK/DM properties of early drug candidates can be evaluated and predicted more accurately, enabling optimized clinical trial design that reduces failure rates and accelerates drug approval.

ATOMIC Platform

MIRROR Platform

RNA Single-Base Editing Tool

Supported by the world‘s largest ADAR substrate editing library with independent IP rights, gRNA (guided RNA) can be designed to achieve accurate and efficient RNA editing by endogenous adenosine deaminase (ADAR). This system enables industry-leading editing efficiency across diverse targets:

95%+ In Vitro Efficiency
80%+ In Vivo Efficiency
SCISSOR Fragment Cutting

SCISSOR Platform

RNA Fragment Excision Tool

A World-First: A proprietary RNA excision technology capable of precisely removing 3-24 nucleotides from target transcript.

This technology provides a novel capability for correcting frameshift mutations and engineering frameshift derived neoantigens, addressing a key technical limitation in current RNA editing approaches.